2. Signaling Pathways
  3. Anti-infection
  4. Parasite

Parasite

Parasite

Related Products

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Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.

Parasite Isoform Specific Products:

Parasite Isoform Comparison
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N6054R
    Niranthin (Standard)
    		Inhibitor
    Niranthin (Standard) is the analytical standard of Niranthin. This product is intended for research and analytical applications. Niranthin, a lignan with a wide spectrum of pharmacological activities. Niranthin is a potent and non-competitive inhibitor of heterodimeric type IB topoisomerase of L. donovani. Niranthin can be used for the research of drug-resistant leishmaniasis research.
    Niranthin (Standard)
  • HY-126114R
    Lupeol acetate (Standard)
    		Inhibitor
    Lupeol acetate (Standard) is the analytical standard of Lupeol acetate. This product is intended for research and analytical applications. Lupeol acetate is a derivative of Lupeol. Lupeol acetate is an anti-inflammatory, antibacterial, anti-trypanosomic and anticancer agent with oral activity. Lupeol acetate significantly improves the symptoms of rheumatoid arthritis by down-regulating the expression of inflammatory cytokines and osteoclast production. Lupeol acetate inhibits spermatogenesis in male rats and eventually led to infertility.
    Lupeol acetate (Standard)
  • HY-N7926R
    Pentadecane (Standard)
    		Inhibitor
    Pentadecane (Standard) is the analytical standard of Pentadecane. This product is intended for research and analytical applications. Pentadecane is a floral volatile antimalarial agent that can inhibit the growth of parasites such as Leishmania and avoid infection of macrophages. The IC50s of Pentadecane against promastigotes and amastigotes are 65.3 μM and 60.5 μM, respectively. Pentadecane also has anti-inflammatory, analgesic, and antipyretic activities.
    Pentadecane (Standard)
  • HY-160985
    Lemidosul
    Lemidosul is an anti-trypanosomiasis compound that can be further optimized for its performance as an anti-trypanosomiasis drug by means of a computer-aided drug design (CADD) approach.
    Lemidosul
  • HY-B2015R
    Carbosulfan (Standard)
    		Inhibitor
    Carbosulfan (Standard) is the analytical standard of Carbosulfan. This product is intended for research and analytical applications.
    Carbosulfan (Standard)
  • HY-N7648
    Atherosperminine
    		Inhibitor
    Atherosperminine (Atherospermine) is a nature occurring alkaloid, has antiplasmodial activities in vitro, with an IC50 of 5.80 μM. Atherosperminine is a good reductant with the ability to chelate metals. Atherosperminine has scavenging activity towards the free radical DPPH, with an IC50 of 29.56 μg/mL. Atherosperminine exerts a non-specific relaxant effect on the trachealis.
    Atherosperminine
  • HY-124431
    Kikumycin A
    		Inhibitor
    Kikumycin A is an antibiotic, which can be generated from Streptomyces. Kikumycin A exhibits antibacterial activity against Gram-positive and Gram-negative bacteria. Kikumycin A exhibits antitrichomonal activity, with MIC of 25 μg/mL for Trichomonas foetus.
    Kikumycin A
  • HY-N0444R
    Rubiadin (Standard)
    		Inhibitor
    Rubiadin (Standard) is the analytical standard of Rubiadin. This product is intended for research and analytical applications. Rubiadin is a dihydroxy anthraquinone isolated from Rubia cordifolia. Rubiadin has a potent antixidant activity.
    Rubiadin (Standard)
  • HY-W050154S
    Kojic acid-13C6
    		Inhibitor
    Kojic acid-13C6 is 13C labeled Kojic acid (HY-W050154). Kojic acid is a substance produced by Aspergillus oryzae that is orally effective and can also be absorbed transdermally. Kojic acid exhibits various biological activities, including anti-aging, anti-nematode, antimicrobial, antioxidant, and anti-inflammatory effects. Kojic acid is a Tyrosinase inhibitor with an Mushroom Tyrosinase IC50 of 182.7 μM. Kojic acid prevents melanin production by capturing copper ions that bind to the tyrosinase active site, thus inhibiting its activation. Kojic acid also suppresses the NF-κB and p21 signaling pathways in human keratinocytes. Kojic acid derivatives have anticancer activity.
    Kojic acid-<sup>13</sup>C<sub>6</sub>
  • HY-N14364
    Flavipucine
    		Inhibitor
    Flavipucine (Flavipucin), a glutarimide antibiotic, is found in the strain of Aspergillus flavipes F-2090/7. Flavipucine has antibacterial activity against B. subtilis. Flavipucine has antiprotozoal activity. Flavipucine has cytotoxic activity against several cancer cells.
    Flavipucine
  • HY-17437R
    Mefloquine (Standard)
    		Inhibitor
    Mefloquine (Standard) is the analytical standard of Mefloquine. This product is intended for research and analytical applications. Mefloquine (Mefloquin), an orally active and potent quinoline antimalarial agent, is an anti-SARS-CoV-2 entry inhibitor. Mefloquine is also a K+ channel (KvQT1/minK) antagonist with an IC50 of ~1 μM. Mefloquine can be used for malaria, systemic lupus erythematosus and cancer research.
    Mefloquine (Standard)
  • HY-N15413
    Thalidasine
    		Inhibitor
    Thalidasine (compound 3) is a bisbenzyltetrahydroisoquinoline alkaloid. Thalidasine is a anticancer agent against human colon adenocarcinoma cells. Thalidasine exhibits antileishmanial activity and can be used for Leishmania infection research research.
    Thalidasine
  • HY-P1991
    Isariin D
    		Inhibitor
    Isariin D is a cyclodepsipeptide isolated from the fungus Isaria felina, which exhibits significant insecticidal activity against Galleria mellonella larvae.
    Isariin D
  • HY-N15041
    Hitachimycin
    		Inhibitor
    Hitachimycin is a macrolide antibiotic that can inhibit tumor cell growth and antiprotozoal effects.
    Hitachimycin
  • HY-B2066R
    Clofentezine (Standard)
    		Inhibitor
    Clofentezine (Standard) is the analytical standard of Clofentezine. This product is intended for research and analytical applications. Clofentezine is a growth inhibitor that is highly lethal to mites.
    Clofentezine (Standard)
  • HY-175364
    Antiparasitic agent-27
    		Inhibitor
    Antiparasitic agent-27 (Compound 2) is a potent antiparasitic agent targeting Leishmania infantum (IC50=3.1 μM). Antiparasitic agent-27 induces G0/G1 cell cycle arrest and reactive oxygen species (ROS) generation to trigger programmed cell death. Antiparasitic agent-27 is promising for research of visceral leishmaniasis (VL).
    Antiparasitic agent-27
  • HY-B0357A
    Diclazuril potassium
    		Inhibitor
    Diclazuril (R-64433) potassium, a benzeneacetonitrile derivative, is a potent and orally active anticoccidial agent. Diclazuril potassium can be used for the research of certain infectious and parasitic diseases, including coccidiosis, acute toxoplasmosis, equine protozoal pyoencephalitis (EPM) et.al.
    Diclazuril potassium
  • HY-N8691
    2',6'-Dihydroxy-4'-methoxydihydrochalcone
    		Inhibitor
    2',6'-Dihydroxy-4'-methoxydihydrochalcone is an orally active dihydrochalcone compound with antiplasmodial and anti-inflammatory activities. 2',6'-Dihydroxy-4'-methoxydihydrochalcone reduces the IL-1β, TNF, and nitrite levels in vitro.
    2',6'-Dihydroxy-4'-methoxydihydrochalcone
  • HY-125632
    Ro 19-9638
    		Inhibitor
    Ro 19-9638 is the major metabolite of Ro 15-0216. Ro 19-9638 exhibits antiparasitic efficacy against Trypanosoma brucei rhodesiense with an IC50 of 0.0341 µg/mL.
    Ro 19-9638
  • HY-N0052AR
    Sanguinarine chloride (Standard)
    		Inhibitor
    Sanguinarine (chloride) (Standard) is the analytical standard of Sanguinarine (chloride). This product is intended for research and analytical applications. Sanguinarine (Sanguinarin) chloride, a benzophenanthridine alkaloid derived from the root of Sanguinaria Canadensis, can stimulate apoptosis via activating the production of reactive oxygen species (ROS). Sanguinarine-induced apoptosis is associated with the activation of JNK and NF-κB.
    Sanguinarine chloride (Standard)
Parasite Isoform Comparison

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