2. Signaling Pathways
  3. Anti-infection
  4. Parasite

Parasite

Parasite

Related Products

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Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.

Parasite Isoform Specific Products:

Parasite Isoform Comparison
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-B2186R
    Piperazine adipate (Standard)
    		Inhibitor
    Piperazine adipate (Standard) is the analytical standard of Piperazine adipate. This product is intended for research and analytical applications. Piperazine adipate is a potent broad spectrum anthelmintic against many common worm infections in mammals.
    Piperazine adipate (Standard)
  • HY-B1953S
    Thiacloprid-d4
    Thiacloprid-d4 is the deuterium labeled Thiacloprid. Thiacloprid, a chloronicotinyl insecticide, is targeted chiefly to control aphid pest species in orchards and vegetables. Thiacloprid destabilizes DNA. Thiacloprid changes the structure and stability of DNA through binding into the minor groove by hydrophobic or hydrogen interactions.
    Thiacloprid-d<sub>4</sub>
  • HY-12639
    Bephenium
    		Inhibitor
    Bephenium is an anthelmintic agent formerly used in the treatment of hookworm infections and ascariasis; B-type AChR activator.
    Bephenium
  • HY-145287A
    S-MGB-234 TFA
    S-MGB-234 TFA is a minor groove binder used for African Animal Trypanosomiasis (AAT). S-MGB-234 exhibits excellent in vitro activity against the primary pathogens of AAT: Trypanosoma congolense and Trypanosoma vivax. S-MGB-234 TFA does not show cross-resistance with current diamidine active molecules and is not internalized via the transporters used by diamidines.
    S-MGB-234 TFA
  • HY-176253
    Antitrypanosomal agent 26
    		Inhibitor
    Antitrypanosomal agent 26 (Compound 1) is an allosteric trypanosome alternative oxidase (TAO) inhibitor. Antitrypanosomal agent 26 exhibits potent activity against African animal trypanosomes (e.g., Trypanosoma brucei, etc.) with an IC50 value of 1.3 nM for recombinant TAO. Antitrypanosomal agent 26 blocks the mitochondrial electron transport chain of trypanosomes and inhibits glucose-dependent respiration. Antitrypanosomal agent 26 is promising for research of African animal trypanosomiasis, such as bovine trypanosomiasis.
    Antitrypanosomal agent 26
  • HY-13735BR
    Quinacrine hydrochloride hydrate (Standard)
    		Inhibitor
    Quinacrine (hydrochloride hydrate) (Standard) is the analytical standard of Quinacrine (hydrochloride hydrate). This product is intended for research and analytical applications. Quinacrine hydrochloride hydrate (Mepacrine hydrochloride hydrate) is an antimalarial agent, which possess anticancer effect both in vitro and vivo. Quinacrine hydrochloride hydrate suppresses NF-κB and activates p53 signaling, which results in the induction of the apoptosis.
    Quinacrine hydrochloride hydrate (Standard)
  • HY-B1467R
    Domiphen bromide (Standard)
    		Inhibitor
    Domiphen bromide (Standard) is the analytical standard of Domiphen bromide (HY-B1467). This product is intended for research and analytical applications. Domiphen bromide is a cationic active quaternary ammonium salt and also an inhibitor of HERG channels (IC50: 9 nM), aminopeptidase-like enzymes, Escherichia coli alkaline phosphatase, and α-chymotrypsin. Domiphen bromide has multiple activities such as antibacterial, antimalarial, and disinfectant properties, and it is also a synergist of Colistin (HY-113678). Domiphen bromide can be used as a chemical preservative and a cationic surfactant, and it can also be used in the research of bacterial infectious diseases such as pharyngitis, thrush, and oral ulcers.
    Domiphen bromide (Standard)
  • HY-W714863
    Arohynapene B
    		Inhibitor
    Arohynapene B is an anticoccidial compound that inhibits the growth of Eimeria tenella.
    Arohynapene B
  • HY-14830
    SAR 97276
    		Inhibitor 98.05%
    SAR 97276 (Albitiazolium bromide) is an antimalarial agent. SAR 97276 interfers with the phospholipid metabolism of malarial parasites, especially the biosynthesis of phosphatidylcholine (PC). SAR 97276 enters erythrocytes through the new permeability pathways (NPP) of infected erythrocytes, and is transported into the malarial parasite by a poly-specific cation carrier.
    SAR 97276
  • HY-W777995
    Clindamycin B
    		Inhibitor
    Clindamycin B is a derivative of Clindamycin (HY-B1455).
    Clindamycin B
  • HY-119556
    Butonate
    		Inhibitor
    Butonate is an insecticide. Butonate is an orally active anthelmintic.
    Butonate
  • HY-137968
    Avermectin B1a aglycon
    		Inhibitor
    Avermectin B1a aglycon is an aglycone derivative of Avermectin B1a (HY-15308), an antiparasitic agent that paralyzes nematodes. Avermectin B1a aglycon hyperpolarizes P. crassipes muscle fibers, with a minimum effective concentration of 0.1 μM.
    Avermectin B1a aglycon
  • HY-W437569
    Melicopine
    		Inhibitor
    Melicopine is an alkaloid found in Z. simulans with antimalarial and anticancer activities. It exhibits inhibitory activity against chloroquine-sensitive 3D7 and chloroquine-resistant Dd2 strains of P. falciparum, with IC50 values of 29.7 and 33.7 µg/mL, respectively. Melicopine is cytotoxic to prostate cancer cells PC-3M and LNCaP (IC50 values of 47.9 and 37.8 µg/mL), but has no effect on non-cancerous HEK293 cells (IC50 greater than 100 µg/mL). Melicopine holds promise for research in anticancer and anti-infection fields.
    Melicopine
  • HY-D0143A
    Quinine dihydrochloride
    		Inhibitor
    Quinine dihydrochloride is an orally active alkaloid extracted from cinchona bark and can be used in anti-malarial studies. Quinine dihydrochloride is a potassium channel inhibitor that inhibits WT mouse Slo3 (KCa5.1) channel currents evoked by voltage pulses to +100 mV with an IC50 of 169 μM.
    Quinine dihydrochloride
  • HY-B0295R
    Chloroxine (Standard)
    		Inhibitor
    Chloroxine (Standard) is the analytical standard of Chloroxine. This product is intended for research and analytical applications. Chloroxine is one of the important 8-hydroxyquinoline derivative. Chloroxine has effective antibacterial, antifungal, antiprotozoal and antiamoebic activities, especially used in treating the intestinal amebiasis. Chloroxine is also used in the treatment of dandruff and seborrheic dermatitis of the scalp.
    Chloroxine (Standard)
  • HY-117986
    AB 3217-A
    		Inhibitor
    AB 3217-A, an anti-mite substance, can be isolated from the fermentation broth of a streptomycete strain.
    AB 3217-A
  • HY-119707
    TDR 32750
    		Inhibitor
    TDR 32750 is an antimalarial agent. TDR 32750 inhibits P. falciparum activity with an ED50 value of 0.014 μM.
    TDR 32750
  • HY-174130
    PI4Kβ/PKG-IN-1
    		Inhibitor
    PI4Kβ/PKG-IN-1 (Compound 19) is an orally active dual inhibitor targeting Plasmodium phosphatidylinositol 4-kinase beta (PI4Kβ) and cGMP-dependent protein kinase (PKG). PI4Kβ/PKG-IN-1 exhibits potent antiplasmodial activity. PI4Kβ/PKG-IN-1 is promising for research of malaria.
    PI4Kβ/PKG-IN-1
  • HY-B1113R
    Diazinon (Standard)
    		Inhibitor
    Diazinon (Standard) is the analytical standard of Diazinon. This product is intended for research and analytical applications.
    Diazinon (Standard)
  • HY-W079315
    5-Phenylthieno[2,3-d]pyrimidin-4-amine
    5-Phenylthieno[2,3-d]pyrimidin-4-amine (Compound 3b) is a heterocyclic compound with antiviral and antiprotozoal activities.
    5-Phenylthieno[2,3-d]pyrimidin-4-amine
Parasite Isoform Comparison

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