2. Signaling Pathways
  3. Anti-infection
  4. Parasite

Parasite

Parasite

Related Products

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Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.

Parasite Isoform Specific Products:

Parasite Isoform Comparison
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-17035R
    Doramectin (Standard)
    		Inhibitor
    Doramectin (Standard) is the analytical standard of Doramectin. This product is intended for research and analytical applications. Doramectin is a derivative of Ivermectin (HY-15310). Doramectin is a potent antiparasitic antibiotic. Doramectin is an active compound against S.mansoni in an NMRI mouse infection model.
    Doramectin (Standard)
  • HY-173027
    SPB07935
    		Inhibitor
    SPB07935 inhibits the plasmepsin II in Plasmodium falciparum and can be used as an antimalarial agent. SPB07935 regulates the life cycle of P. falciparum, inhibits the growth of Plasmodium strains FcB1 and 3D7 with IC50 of 8 μM and 4.7 μM.
    SPB07935
  • HY-P1638
    Isariin A
    		Inhibitor
    Isariin A is a cyclodepsipeptide isolated from the fungus Isaria cretacea, which exhibits antimalarial activity.
    Isariin A
  • HY-129130
    Canthin-6-one N-oxide
    		Inhibitor
    Canthin-6-one N-oxide (Canthin-6-one 3-oxide) is an orally active antiparasitic agent with limited activity.
    Canthin-6-one N-oxide
  • HY-16973S3
    Fluralaner-d5
    		Inhibitor
    Fluralaner-d5 (A1443-d5) is deuterium labeled Fluralaner. Fluralaner (INN) is a systemic insecticide and acaricide Fluralaner through potent blockage of GABA and L-glutamate gated chloride channels.
    Fluralaner-d<sub>5</sub>
  • HY-133709
    β-Aflatrem
    		Inhibitor
    β-Aflatrem is an insecticide metabolite from the sclerotium of Aspergillus flavus that exhibits significant activity against the corn borer H. zea.
    β-Aflatrem
  • HY-B1118R
    Secnidazole (Standard)
    		Inhibitor
    Secnidazole (Standard) is the analytical standard of Secnidazole. This product is intended for research and analytical applications. Secnidazole (RP-14539) is an orally active azole antibiotic and a imidazole mitigator of Serratia marcescens virulence. Secnidazole, as an analog of acylhomoserine lactones, effectively inhibits QS resulting in the attenuation of Pseudomonas aeruginosa pathogenesis. Secnidazole has antimicrobial activity against many anaerobic Gram-negative and Gram-positive bacterial species in vitro. Secnidazole can be used for the research of various diseases, such as amoebiasis and giardiasis, and bacterial vaginitis.
    Secnidazole (Standard)
  • HY-173213
    Antileishmanial agent-33
    		Inhibitor
    Antileishmanial agent-33 (4e), a hybrid compound of grandisin and machilin G, shows moderate activity on promastigotes (IC50 of 38.1 μM). Antileishmanial agent-33 (4e) shows potential as an antileishmanial agent for the research of cutaneous leishmaniasis (CL).
    Antileishmanial agent-33
  • HY-B1881R
    Pirimiphos-methyl (Standard)
    		Inhibitor
    Pirimiphos-methyl (Standard) is the analytical standard of Pirimiphos-methyl. This product is intended for research and analytical applications. Pirimiphos-methyl is a rapid-acting organophosphorus insecticide and acaricide, causing inhibition of AChE in target organisms. Pirimiphos-methyl is often used for prevention and control of beetles, snout beetles, moths and Ephestia cautella during storage of agricultural grains.
    Pirimiphos-methyl (Standard)
  • HY-W663938
    Cyflumetofen
    		Inhibitor
    Cyflumetofen is a synthetic miticide that strongly inhibits mitochondrial complex II of spider mites, but not of insects, crustaceans, or mammals. Cyflumetofen is not significantly effective in inhibiting aflatoxin production in fungi.
    Cyflumetofen
  • HY-107566A
    Conessine dihydrobromide
    		Inhibitor
    Conessine dihydrobromide is an orally active and BBB-penatrable selective histamine H3 receptor antagonist. The pKi values of Conessine dihydrobromide for rat and human H3 receptors are 7.61 and 8.27, respectively. Conessine dihydrobromide is an inhibitor of the multidrug efflux pump system in Pseudomonas aeruginosa and can enhance the activity of antibiotics. Conessine dihydrobromide has antimalarial activity. Conessine dihydrobromide can also be used in the research of muscle atrophy.
    Conessine dihydrobromide
  • HY-116535B
    DL-threo-PPMP
    DL-threo-PPMP is an inhibitor of sphingosine synthetase in Plasmodium falciparum. DL-threo-PPMP inhibits the activity of sphingosine synthetase by mimicking the substrate sphingosine. This inhibition leads to a rapid decrease in the activity of sensitive sphingosine synthetase, selectively destroying the interconnected tubular network of TVMs in the host cell cytoplasm, and this inhibition also blocks the proliferation of Plasmodium falciparum. DL-threo-PPMP can be used for the study of Plasmodium biology and the search for new antimalarial strategies.
    DL-threo-PPMP
  • HY-165123
    Mepartricin
    		Inhibitor
    Mepartricin is a polyene macrolide with antifungal and antiprotozoal activities, widely used in research related to benign prostatic hyperplasia.
    Mepartricin
  • HY-13702R
    Nilutamide (Standard)
    		Inhibitor
    Nilutamide (Standard) is the analytical standard of Nilutamide. This product is intended for research and analytical applications. Nilutamide (Nilandron) is an orally active nonsteroidal androgen receptor antagonist with affinity for androgen receptors but not for progestogen, estrogen or glucocorticoid receptors. Nilutamide can be used to research prostate cancer. Nilutamide also has antischistosomal properties.
    Nilutamide (Standard)
  • HY-19285AR
    Sulfaclozine (sodium) (Standard)
    		Inhibitor
    Sulfaclozine (sodium) (Standard) is the analytical standard of Sulfaclozine (sodium). This product is intended for research and analytical applications. Sulfaclozine sodium (Sulfachloropyrazine sodium) is an efficacious sulphonamide derivative with antibacterial and anticoccidial effects. Sulfaclozine sodium is commonly used for the treatment of various poultry diseases (particularly, collibacteriosis, fowl cholera and coccidiosis).
    Sulfaclozine (sodium) (Standard)
  • HY-B0879AR
    Suramin (sodium salt) (Standard)
    		Inhibitor
    Suramin (sodium salt) (Standard) is the analytical standard of Suramin (sodium salt). This product is intended for research and analytical applications. Suramin sodium salt (Suramin hexasodium salt) is a reversible and competitive protein-tyrosine phosphatases (PTPases) inhibitor. Suramin sodium salt is a potent inhibitor of sirtuins: SirT1 (IC50=297 nM), SirT2 (IC50=1.15 μM), and SirT5 (IC50=22 μM). Suramin sodium salt is a competitive inhibitor of reverse transcriptase (DNA topoisomerase II: IC50=5 μM). Suramin sodium salt is a potent SARS-CoV-2 RNA-dependent RNA polymerase (RdRp) inhibitor. Suramin sodium salt efficiently inhibits IP5K and is an antiparasitic, anti-neoplastic and anti-angiogenic agent.
    Suramin (sodium salt) (Standard)
  • HY-122461
    Glycobiarsol
    		Inhibitor
    Glycobiarsol is an organic arsenical compound, which can be used as an amoebicidal agent. Glycobiarsol exhibits toxicity and side effects.
    Glycobiarsol
  • HY-113907
    SDZ-285604
    		Inhibitor
    SDZ-285604 (VNF) is a T. cruzi CYP51 inhibitor and can be used for study of Trypanosoma cruzi infection.
    SDZ-285604
  • HY-14895
    Fabomotizole
    		Inhibitor 99.96%
    Fabomotizole (CM346) is an insecticide with anxiolytic, antianxiety, and neuroprotective activities and a substrate of p-glycoprotein. Fabomotizole inhibits the ST-segment depression induced by isoproterenol in a rat model of acute subendocardial ischemia. Fabomotizole also inhibits Giardia lamblia and has the potential to inhibit giardiasis. Fabomotizole also targets Sigma1R, NRH:quinone reductase 2 (NQO2), and MAO-A to exert anxiolytic effects.
    Fabomotizole
  • HY-107483R
    Cambendazole (Standard)
    Cambendazole (Standard) is the analytical standard of Cambendazole. This product is intended for research and analytical applications. Cambendazole is one of the most effective agents for the research of human strongyloidiasis and .
    Cambendazole (Standard)
Parasite Isoform Comparison

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